个人简介
孟永宏，博士，教授，博士生导师，陕西师范大学食品工程与营养科学学院院长，科技部国家科技创新创业人才和中组部“万人计划”创业领军人才，中国食品工业协会科技创新领军人物。主要从事果蔬功能成分的高效生物制造、作用机制解析及其高值化利用研究。兼任中国化工学会生物化工专业分委会委员，中国食品科学技术学会果蔬分会常务委员，陕西省食品科学技术学会秘书长，西部果品资源高值利用(教育部)工程中心主任，《中国油脂》杂志编委，Food Innovation Advances青年编委等。近年来以一作或通讯作者发表SCI论文50余篇;获批发明专利40余件;鉴定科技成果3项;参编专著3部。主持国家重点研发计划课题1项、子课题2项，国家自然基金面上项目2项，科技部863项目1项，军委-教育部装备预研项目1项，教育部博士点基金和陕西省重点研发计划等课题6项。获教育部国家级一流本科课程1项、陕西省科技进步一等奖1项、陕西省科学技术二等奖、三等奖各1项。
近五年科研项目(10万以上)
(1)国家自然科学基金面上项目，32172145，2022.01-2025.12，主持。
(2)国家重点研发计划项目课题，2023YFB4203502，2023.12-2027.11，主持。
(3)苹果幼果多酚提取产业化生产技术，横向，主持。
(4)山地苹果贮藏减损及高值加工技术开发，横向，主持。
近五年代表性学术论文
(1) Yan Lu,Chao Qun Zhang, Xiao Mei Xu, Wen Bin Zhu,Ching Yuan Hu,Tian Gong, Yong Hong Meng*. Novel Methylenetransferase from Human Gut Strain L longoviformis Initiates Sesamin Conversion and Its Catalytic Mechanism[J]. Journal of Agricultural and Food Chemistry, 2026, 74(3): 2850-2864.
(2) Wen Bin Zhu,Tian Gong, Xue Yan Yang, Chao Qun Zhang,Ching Yuan Hu,Lin Shan Shi, Yan Hui Han, Yong Hong Meng*. Heat-treated lacquer seed protein isolate as an efficient emulsion stabilizer enhances curcumin protection and delivery via a‘gastric shield-intestinal release’ mechanism[J]. Food Innovation and Advances,2025,4(4):525-536.
(3) Zi Yao Yu, Wen Bin Zhu, Han Gao, Ching Yuan Hu, Chao Qun Zhang, Yong Hong Meng*. Rubisco-Centric Strategies for Carbon Conservation in Synthetic Biology[J]. Journal of Agricultural and Food Chemistry, 2025, 73(41): 25691-25708.
(4) Huai Qi Shang, Qing Bo Yang, Shan Qiang, Rong Zheng, Chao Qun Zhang,Ching Yuan Hu, Qi Hang Chen, Yong Hong Meng*. Engineering Caffeic Acid O-Methyltransferase for Efficient De Novo Ferulic Acid Synthesis. Engineering in Life Sciences[J].2025,25(4):e70018.
(5) Xiao Fu, Chi Zhang, Xiao Tong Lu, Fang Xiao Guo, Xu Zhang, Huixia Zhou,Xin-Ai Guo, Xiaoyu Wang, Ching Yuan Hu, Shuai Zhang, Yong Hong Meng*.Oil-based micro-sized extraction system designed from O/W Pickering emulsion template for highly efficient nanoplastics removal in the gastrointestinal tract[J]. Food Hydrocolloids,2025,166:111366.
(6) Tian Gong, Ching Yuan Hu, Chao Qun Zhang, Qing Bo Yang, Rong Zheng,Yu Rong Guo*, Yong Hong Meng*. Catalytic Mechanism of Gut Benzyl Ether Reductase for Efficient Bioconversion of Furofuran Lignans into Enterolignan Precursors[J]. Journal of Agricultural and Food Chemistry, 2025, 73(11): 6772-6784.
(7) Zhang Shuqing, Wang Xiaoyu, Liu Shilin, Hu Ching Yuan, Meng Yong Hong*. Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in high-fat and high-fructose diet-induced obese male mice[J]. Brain,Behavior,and Immunity,2025,123:193-210.
(8) Shen lin Liu, Ya long Lu, Dan Tian, Ting ting Zhang, Chao Qun Zhang,Ching Yuan Hu, Ping Chen, and Yong Hong Meng*. Hydroxytyrosol Alleviates Obesity-Induced Cognitive Decline by Modulating the Expression Levels of Brain-Derived Neurotrophic Factors and Inflammatory Factors in Mice[J]. Journal of Agricultural and Food Chemistry, 2024, 72(12): 6250-6264.
(9) Zheng Rong, Chen Qi Hang, Yang Qing Bo, Tian Gong, Ching Yuan Hu,Yong Hong Meng*. Engineering a Carotenoid Cleavage Oxygenase for Coenzyme-Free Synthesis of Vanillin from Ferulic Acid[J]. Journal of Agricultural and Food Chemistry,2024,72:12209-12218.
(10) Chi Zhang, Tian Gong, Shan Qiang, Xiao Yu Wang, Xiao Ru Wang, Shuai Zhang, Yong Hong Meng*. A clean label O/W pickering emulsion stabilized by pectin-containing lignocellulosic nanofibrils isolated from apple pomace[J]. Food Hydrocolloids,2023,150(2024):109583.
(11) Zhang Shuai, Chen Rongqiang, Ding Chenfeng, Tian Gong, Sun jiaojiao, Li Fengchen, Zhang Chaoqun,.Wang Xiaoyu, Guo Yurong, Zhong Tuhua, Meng Yong Hong*. Fabraction of edible bio-nanocomposite coatings from pectin-containing lignocellulosic nanofibers isolated from apple pomace[J]. International Journal of Biological Macromolecules,2024,279:135030.
(12) Tian Dan, Liu Shenlin, Lu Yalong, Zhang Tingting, Wang Xue, Zhang Chaoqun, Hu Chingyuan, Chen Ping, Deng Hong, Meng Yong Hong*Low-methoxy-pectin and chlorogenic acid synergistically promote lipolysis andβ-oxidation by regulating AMPK signaling pathway in obese mice[J]. International Journal of Biological Macromolecules, 2024, 280: 135552.
(13) Liu Liang, Shi Linshan, Hu Chingyuan, Tian Gong, Yang Xueyan, Zhang Chaoqun, Meng Yong Hong*. Walnut protein isolate based emulsion as a promising delivery system enhanced lutein bioaccessibility[J]. International Journal of Biological Macromolecules,2024,275:133608.
(14) Liang Liu,Tian Gong,Ching Yuan Hu, Hong Deng, Yong Hong Meng*ZNF1 up-regulation improves aroma profile by activating carbohydrate metabolism-associated pathways in Saccharomyces cerevisiae WFC-SC-071[J]. Food Bioscience,2023,56:103337.
(15) Yan Yi Qi, Tian Gong, Peng Tao Zhao, Yong Jie Niu, Yong Yuan Hu, Ching Yuan Hu, Shuai Zhang, Yong Hong Meng*. Hydroxytyrosyl oleate is a promising safe additive to inhibit the oxidation of olive oil[J]. Food Control, 2023, 153: 109895.
(16) Lin Shan Shi, Xue Yan Yang, Tian Gong, Ching Yuan Hu, Ye Hua Shen,Yong Hong Meng*. Ultrasonic treatment improves physical and oxidative stabilities of walnut protein isolate-based emulsion by changing protein structure[J]. LWT-Food Science and Technology, 2023, 173:114269.
(17) Qi Hang Chen, Ya Dan Qian, Yong Jie Niu, Ching Yuan Hu, Yong Hong Meng*. Characterization of an efficient CRISPR-iCas9 system in Yarrowia lipolytica for the biosynthesis of carotenoids[J]. Applied Microbiology and Biotechnology, 2023,107:6299-631.
(18) Liang Liu,Peng Tao Zhao, Ching Yuan Hu, Dan Tian, Hong Deng, Yong Hong Meng*. Screening low-methanol and high-aroma produced yeasts for cider fermentation by transcriptive characterization[J]. Frontiers in Microbiology, 2022,13:1042613.
(19) Jia Rui Liang, Hong Deng, Ching Yuan Hu, Peng Tao Zhao and Yong Hong Meng*. Vitality, fermentation, aroma profile, and digestive tolerance of the newly selected Lactiplantibacillus plantarum and Lacticaseibacillus paracasei in fermented apple juice[J]. Frontiers in Nutrition, 2022,9:1045347.
(20) Xue Yan Yang, Lin Shan Shi,Tian Gong, Ching Yuan Hu, Yu Rong Guo,Yong Hong Meng*. Structural modification induced by heat treatments improves the emulsifying attributes of lacquer seed protein isolate[J]. International Journal of Biological Macromolecules,2022,222:1700-1708.
(21) Ting Yuan Qiu, Tian Gong, Shuai Zhang, Qi Hang Chen, Ching Yuan Hu,Yong Hong Meng*. A carbon-carbon hydrolase from human gut probiotics Flavonifractor plautii catalyzes phloretin conversion[J]. Food Bioscience, 2022, 50:102178.
(22) Tian Gong,Bang Chen,Ching Yuan Hu,Yu Rong Guo,Ye Hua Shen,Yong Hong Meng*. Resveratrol inhibits lipid and protein co-oxidation in sodium caseinate-walnut oil emulsions by reinforcing oil-water interface[J]. Food Research International,2022,158:111541.
(23) Qihang Chen, Yaqin Jiang, Zhengzhong Kang, Jie Cheng, Xiaochao Xiong,Ching Yuan Hu, and Yong hong Meng*. Engineering a Feruloyl-Coenzyme A Synthase for Bioconversion of Phenylpropanoid Acids into High-Value Aromatic Aldehydes[J]. Journal of Agricultural and Food Chemistry, 2022, 70: 9948-9960.
(24) Shu Qing Zhang, Dan Tian, Ching Yuan Hu, and Yong Hong Meng*Chlorogenic Acid Ameliorates High-fat and High-Fructose Diet-Induced Cognitive Impairment via Mediating the Microbiota-Gut-Brain Axis[J]. Journal of Agricultural and Food Chemistry, 2022,70:2600-2615.
(25) Tian Gong, Dan Tian, Ching Yuan Hu, Yu Rong Guo, Yong Hong Meng*Improving antioxidant ability of functional emulsifiers by conjugating polyphenols to sodium caseinate[J]. LWT-Food Science and Technology, 2022, 154: 112668.
(26) Qi Hang Chen, Dao Tao Xie, Shan Qiang, Ching Yuan Hu1, Yong Hong Meng*. Developing efficient vanillin biosynthesis system by regulating feruloyl-CoA synthetase and enoyl-CoA hydratase enzymes[J]. Applied Microbiology and Biotechnology,2022,106:247-259.
(27) Jia Lei LEI, Ching Yuan HU, Hong DENG, Yu Rong GUO, Yong Hong MENG*. Authentication of fresh apple juice by stable isotope ratios of 8D, 818O and $\delta^{13}$ C[J]. Food Science and Technology, 2022, v42, e71620.
(28) Pengtao ZHAO, Ying ZHANG, Hong DENG, Yonghong MENG*Antibacterial mechanism of apple phloretin on physiological and morphological properties of Listeria monocytogenes[J]. Food Science and Technology, 2022, v42,e55120.
(29) Hong DENG, Pengtao ZHAO, Tiange Yang, Yonghong MENG*. A comparative study of the cloudy apple juice sterilized by high-temperature short-time or high hydrostatic pressure processing: shelf-life, phytochemical, and microbial view[J]. Food Science and Technology, 2022, v42, e63620.
(30) Shuqing Zhang, Chingyuan Hu, Yurong Guo, Xiaoyu Wang, Yonghong Meng*. Polyphenols in fermented apple juice: Beneficial effects on human health[J].Journal of Functional Foods, 2021, 76: 104294.
(31) Fan Yang, Bo Feng, Yong Jie Niu, Ching Yuan Hu, Yong Hong Meng*.Fu instant tea ameliorates fatty liver by improving microbiota dysbiosis and elevating short-chain fatty acids in the intestine of mice fed a high-fat diet[J]. Food Bioscience,2021,42:101207.
(32) Fan Yang, Liang Liu, Shan Qiang, Ching Yuan Hu, Ying Li, Yong Hong Meng*. Enhanced b-carotene production by overexpressing the DID2 gene, a subunit of ESCRT complex, in engineered Yarrowia lipolytica[J]. Biotechnology Letters,2021,43:1799-1807.
(33) Liang Liu, Yu Ling Qu, Gui Ru Dong, Jing Wang, Ching Yuan Hu and Yong Hong Meng*. Elevatedβ-Carotene Production Using Codon-Adapted CarRA&B and Metabolic Balance in Engineered Yarrowia lipolytica[J]. Frontiers in Microbiology 2021,12,627150.
(34) Yuling QU, Daotao XIE, Chingyuan HU, Hong DENG, Yonghong MENG*. Direct steam injection pretreatment improves microwave-assisted extraction yield for total flavonoids and myricetin from Hovenia dulcis Thunb[J]. Food Science and Technology,2021,41:334-342.
近五年获奖
(1)教育部国家级一流本科课程，排名1，2025年
(2)陕西省科学技术进步一等奖，排名3，2025年
(3)第六届陕西本科高校教师创新大赛三等奖，排名1，2025年
(4)陕西师范大学第七届“红烛杯”教师教学创新大赛校级决赛一等奖，排名1，2024年
(5)陕西省科技工作者创新创业大赛三等奖，排名2，2023年
近五年专利
(1)孟永宏,师琳珊,李封辰,杨雪言,张帅,路亚龙.一种具有良好乳化性能的核桃多肽及其制备方法[P].ZL202111548661.4，授权日期2023-08-15.
(2)孟永宏,杨雪言,李封辰,师琳珊,张帅.一种乳化性能良好的漆籽粕蛋白肽及其制备方法[P].ZL202111548665.2，授权日期2023-08-15.
(3)孟永宏,邱亭媛,郭玉蓉,邓红,李封辰.利用强启动子全合成羟基酪醇的重组解脂亚罗酵母菌的构建方法[P].ZL202110292118.6，授权日期2022-7-15.
(4)孟永宏,杨雪言,郭玉蓉,邓红,李封辰.一种促进重组解脂亚罗酵母菌合成根皮素的方法[P].ZL202110157119.X，授权日期2022-6-17.
(5)孟永宏,苏安平,陈芝,李颖,强珊.一种产番茄红素类球细菌工程菌株及其构建方法[P].ZL201810457895.Y,授权日期2022-4-5.
(6)王静,孟永宏,刘梁,钱亚丹,杨凡.一种产β-胡萝卜素的基因工程菌及其构建方法[P].ZL201811650420.9，授权日期2022-4-5.
(7)孟永宏,张煜瞳,谢道涛,强珊,徐俊杰,田杰生,李颖.一种固体纳米分散体吸波材料[P].ZL201910949343.5，授权日期2021-10-29.
(8)孟永宏,张煜瞳,谢道涛,强珊,徐俊杰,田杰生,李颖.一种基于3D打印技术的结构型宽频带吸波材料的制备方法[P].ZL201910962626.3，授权日期2021-03-23.