教学科研

李照

发布日期:2017-10-01     作者:      分享到:

个人简介

 

李照,副教授,硕士生导师。2009年获得陕西师范大学化学与化工学院学士学位。2014年获得中国科学院化学研究所分析化学博士学位,师从马会民研究员。2015年起任职于陕西师范大学食品工程与营养科学学院,主要从事食品安全检测与控制研究,光学探针的设计合成及其应用的研究。2019年3月至2020年3月在美国Stanford University化学系与Steven G. Boxer 院士进行合作研究,在荧光探针的设计和检测方面取得了许多创新性研究成果。现主持国家自然科学基金项目,陕西省重点研发计划项目,陕西省高校科协青年人才托举计划项目,西安市农业技术研发项目,中央高校重点项目和中央高校优青项目各1项,参与国家自然科学基金项目4项。近年以第一作者或通讯作者身份在Anal. Chem.Chem. Commun.Biosens. Bioelectron.J. Agric. Food Chem.Food Chem.等国际重要学术期刊上发表学术论文40余篇,授权国家专利7项,科研成果获陕西省高等学校科学技术一等奖(第一完成人,2021年)。

 

联系方式:邮箱:lizhao0309@snnu.edu.cnQQ376032706

 

 

代表性成果

1. Qiuyue Wang, Zhao Li*, Yitong Hao, Yuan Zhang and Chengxiao Zhang. Near-infrared fluorescence probe with new recognition moiety for specific detection and imaging of aldehyde dehydrogenase expecting identification and isolation of cancer stem cells. Anal. Chem., 2022, 94, 17328-17333.

2. Ning Ding, Zhao Li*, Yitong Hao and Chengxiao Zhang. Design of a new hydrazine moiety-based near-infrared fluorescence probe for detection and imaging of endogenous formaldehyde in vivo. Anal. Chem., 2022, 94, 12120-12126.

3. Xinwei Tian, Zhao Li*, Yue Sun, Pan Wang and Huimin Ma*. Near-infrared fluorescent probes for hypoxia detection via joint regulated enzymes: design, synthesis, and application in living cells and mice. Anal. Chem., 2018, 90, 13759-13766.

4. Xinwei Tian, Zhao Li*, Ning Ding and Jiahang Zhang. Near-infrared ratiometric self-assembled theranostic nanoprobe: imaging and tracking cancer chemotherapy. Chem. Commun., 2020, 56, 3629-3632.

5. Ning Ding, Zhao Li*, Xinwei Tian, Jiahang Zhang, Kaili Guo and Pan Wang. Azo-based near-infrared fluorescent theranostic probe for tracking hypoxia-activated cancer chemotherapy in vivo. Chem. Commun., 2019, 55, 13172-13175.

6. Jiahang Zhang, Zhao Li*, Xinwei Tian and Ning Ding. A novel hydrosoluble near-infrared fluorescence probe for specifically monitoring of tyrosinase and application in a mouse model. Chem. Commun., 2019, 55, 9463-9466.

7. Dongyu Li, Xinwei Tian, Zhao Li*, Jiahang Zhang and Xingbin Yang. Preparation of a near-infrared fluorescent probe based on IR-780 for highly selective and sensitive detection of bisulfite/sulfite in food, living cells and mice. J. Agric. Food Chem., 2019, 67, 3062-3067.

8. Xinwei Tian, Xinxin Tong, Zhao Li*, Dongyu Li, Qingjun Kong* and Xingbin Yang. In vivo fluoride ion detection and imaging in mice using a designed near-infrared ratiometric fluorescent probe based on IR-780. J. Agric. Food Chem., 2018, 66, 11486-11491.

9. Xinwei Tian, Zhao Li*, Yaxing Pang, Dongyu Li and Xingbin Yang*, Benzoyl Peroxide Detection in Real Samples and Zebrafish Imaging by a Designed Near-Infrared Fluorescent Probe. J. Agric. Food Chem., 2017, 65, 9553-9558.

10. Dongyu Li, Zhao Li*, Weihua Chen and Xingbin Yang*, Imaging and detection of carboxylesterase in living cells and zebrafish pretreated with pesticides by a New near-infrared fluorescence off-on probe. J. Agric. Food Chem., 2017, 65, 4209-4215.

11. Ning Ding, Zhao Li*, Yitong Hao and Xingbin Yang*. A new amine moiety-based near-infrared fluorescence probe for detection of formaldehyde in real food samples and mice. Food Chem., 2022, 384, 132426.

12. Xiaojie Tang, Zhao Li*, Yangxiong Li, Yuan Zhang, Qiuyue Wang and Chengxiao Zhang*. A new metal-free near-infrared fluorescent probe based on nitrofuran for detection and bioimaging of carbon monoxide releasing molecule-2 in vivo. Analyst, 2022, 147, 268-273.

13. Jiahang Zhang, Liang Shi, Zhao Li*, Dongyu Li, Xinwei Tian and Chengxiao Zhang*. Near-infrared fluorescence probe for hydrogen peroxide detection: design, synthesis, and application in living systems. Analyst, 2019, 144, 3643-3648.

14. Zhao Li, Xinghui Gao, Wen Shi, Xiaohua Li and Huimin Ma*, In vivo detection and imaging of nitroreductase in zebrafish by a new near-infrared fluorescence off-on probe. Biosens. Bioelectron., 2015, 63, 112-116.

15. Zhao Li, Xinghui Gao, Wen Shi, Xiaohua Li and Huimin Ma*, 7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off-on probe for highly sensitive and selective detection of nitroreductase. Chem. Commun., 2013, 49, 5859-5861.

16. Zhao Li, Xiaohua Li*, Xinghui Gao, Yangyang Zhang, Wen Shi and Huimin Ma*, Nitroreductase Detection and Hypoxic Tumor Cell Imaging by a Designed Sensitive and Selective Fluorescent Probe, 7-[(5-Nitrofuran-2-yl)methoxy]-3H-phenoxazin-3-one. Anal. Chem., 2013, 85, 3926-3932.