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袁莉
职称/职务: 副教授
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电子信箱: yuanli112086@snnu.edu.cn
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研究工作简介

2008年7月于甘肃农业大学食品科学与工程学院获得工学学士学位,2011年7月于甘肃农业大学食品科学与工程学院获得工学硕士学位,2014年7月于西北农林科技大学食品科学与工程学院获得工学博士学位,之后于陕西师范大学食品工程与营养科学学院任职。主要从事天然食品因子的营养功能性评价及分子机制研究。

 

代表性成果

1. Li Yuan, Shuping Wei, Jing Wang, Xuebo Liu. Isoorientin induces apoptosis and  autophagy simultaneously by ROS-related P53, PI3K/Akt, JNK and P38 signaling pathways in HepG2 cancer cells. Journal of Agricultural and Food Chemistry.2014,62(23):5390-5400.

2.Li Yuan, Yuchen Wu, Xiaomeng Ren, Qian Liu, Jing Wang, Xuebo Liu. Isoorientin attenuates lipopolysaccharide-induced pro-in?ammatory responses through down-regulation of ROS-related MAPK/NF-KB signaling pathway in BV-2 microglia. Molecular and Cellular Biochemistry. 2014, 386:153-165.

3. Li Yuan, Yutang Wang, Jing Wang, Haifang Xiao, Xuebo Liu. Additive effect of zinc oxide nanoparticles and isoorientin on apoptosis in human hepatoma cell line. Toxicology Letters. 2013,225: 294-304.

4. Li Yuan, Jing Wang, Haifang Xiao, Chunxia Xiao, Wanqiang Wu, Xuebo Liu. MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells. Food and Chemical Toxicology. 2013, 53: 62-68.  

5. Li Yuan, Xiaomeng Ren,Yuchen Wu, Yutang Wang, Jing Wang, Haifang Xiao, Xuebo Liu. Isoorientin protects BRL-3Arat liver cell against hydrogen peroxide-induced apoptosis by inhibiting mitochondrial dysfunction, inactivating MAPKs, activating Akt and scavenging ROS and NO. Biomedicine and Aging Pathology. 2013, 3: 153-159. 

6. Li Yuan, Yang Bi, Yonghong Ge, Yi Wang, Yaoyao Liu, Guolin Li. Postharvest hot water dipping reduces decay by inducing disease resistance and maintaining firmness in muskmelon (Cucumis melo L.) fruit. Scientia Horticulturae. 2013, 161: 101-110. 

7.  Li Yuan, Jing Wang, Haifang Xiao, Chunxia Xiao, Yutang Wang, Xuebo Liu. Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells. Toxicology and Applied Pharmacology. 2012, 265: 83-92.

8. 袁莉,吴雨晨,任骁萌,刘学波. 荭草素和异荭草素抗氧化活性及对肝癌细胞增殖的影响.食品科学技术学报,2013,31(6):21-27.

9. 袁莉,毕阳,葛永红,王毅, 李颖超,尹燕,赵阿梅.采后热处理对厚皮甜瓜贮藏品质的影响.食品科学.2010,31(20):421-424.

10. 袁莉,毕阳,李永才,王毅,李颖超,尹燕,陈松江,丁波.采后赤霉素(GA3)处理对低温贮藏期间枸杞鲜果腐烂的抑制和品质的影响.食品与生物技术学报.2011,30(5).

 

 

 

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